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Challenges in measuring renal function in liver cirrhosis : are there implications in clinical practice?

Journal Volume 83 - 2020
Issue Fasc.4 - Case series
Author(s) J. Carvão 1, J.N. Carvão 2, V. Pereira 1, L. Jasmins 1
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PAGES 633-638
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Affiliations:
(1) Gastroenterology Department, Hospital Central do Funchal, Madeira Island, Portugal
(2) Nephrology Department, Hospital Central do Funchal, Madeira Island, Portugal

Renal dysfunction is frequent in liver cirrhosis, and it is associated with poor prognosis. Currently, there are major limitations when assessing renal function in cirrhotic patients. Available methods are biased and have a tendency to overestimate glomerular filtration rates (GFR) consistently. A subset of new creatinine-based formulas derived specifically from these populations may provide a more accurate estimation of renal function. In this article, we will explore the estimation methods of GFR in cirrhosis available to date and discuss possible implications in clinical practice.

Keywords: kidney, liver cirrhosis, liver transplant.

The authors declare that they have no conflict of interest.
© Acta Gastro-Enterologica Belgica.
PMID 33321021